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BOSTON (江湖电竞最新版比赛(江湖电竞投注app网站)) — Shares of SIGA Technologies Inc. dipped Monday afternoon as the drug sector’s two main indexes moved south.

SIGA SIGA, +2.67%   shares were off 5% at $12.56 after falling as much as 15%.

Over the weekend, SIGA said it may lose a government contract worth up to $2.8 billion for its smallpox medication because the Small Business Administration has determined it was not eligible. The smallpox contract was to be awarded to a small business under the original proposed contract by the Department of Health and Human Services.

SIGA said it plans to appeal the SBA ruling.

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On Oct. 13, SIGA shared soared more than 40% on news that the company had been tentatively awarded the contract.

XenoPort Inc. XNPT   shares rose 7% to $8.59 after the company announced it had amended its collaboration agreement with GlaxoSmithKline PLC GSK, +1.21%   for the drug Horizant.

In February, XenoPort shares were crushed when U.S. regulators declined to approve the product for restless-legs syndrome, citing safety concerns.

Santarus Inc. SNTS, -0.61%   shares advanced 2% after the biotech group announced favorable Phase III clinical data for its compound budesonide MMX in the treatment of ulcerative colitis.

Athersys Inc. ATHX, -3.17%   shares also jumped 6% on ulcerative colitis news. Athersys said U.S. regulators have give the green light for the company to proceed with a Phase II clinical trial testing its stem cell therapy Multistem on patients with the debilitating disease.

Athersys is co-developing the product with Pfizer Inc. PFE, +1.61%  

The NYSE Arca Pharmaceutical Index DRG,   and the NYSE Arca Biotechnology Index BTK, +1.09%   were both marginally lower at 309.94 and 1,168.74, respectively.